PROPER USE OF THIS PRODUCT

Always take Nic-Hit spray as stated in this guide. You should check with your professional health care provider or pharmacist if you are not sure.
Individuals under 18 years of age should not use Nic-Hit spray unless prescribed by a professional health care provider.
Stop smoking completely during treatment with Nic-Hit spray.
The following chart shows the recommended step by step process for taking Nic-Hit spray:

STEP BY STEP PROCESS FOR TAKING NIC-HIT SPRAY

1 mg Nic-Hit spray	2 mg Nic-Hit spray
Step #1: weeks 1-6
pray 1-2 doses, 1-24 times a day, of 1 mg Nic-Hit liquid into your mouth, whenever you would normally smoke a cigarette or have cravings for a cigarette. Use the second spray if your cravings do not disappear within a few minutes. If 2 sprays are required, future doses may be delivered as 2 consecutive sprays. The maximum daily dose is 48 sprays per day providing up to 48 mg of nicotine.	Spray 1 dose, 1-32 times a day, of 2 mg Nic-Hit liquid into your mouth, whenever you would normally smoke a cigarette or have cravings for a cigarette. The maximum daily dose is 32 sprays per day providing up to 64 mg of nicotine.
Step #2: weeks 7-9
Start reducing the number of sprays per day. By the end of week 9 you should be using half the average number of sprays per day that you used in step #1.	Start reducing the number of sprays per day. By the end of week 9 you should be using half the average number of sprays per day that you used in step #1.
Step #3: weeks 10-12
Continue reducing the number of sprays per day so that you are not using more than 2-4 sprays per day during week 12. At the end of week 12, stop using the Nic-Hit spray	Continue reducing the number of sprays per day so that you are not using more than 2-4 sprays per day during week 12. At the end of week 12, stop using the Nic-Hit spray.

You may be tempted to smoke again after treatment has stopped. If you have a craving use 2 sprays if one spray does not help within a few minutes.
Normally you should take Nic-Hit spray for 3 months but not longer than 6 months. Consult your professional health care provider or pharmacist if you need to use the Nic-Hit spray for longer than 6 months. Save any remaining doses of the spray as craving for smoking may suddenly occur.

WHAT TO DO BEFORE USING THIS PRODUCT
(RISK INFORMATION AND CAUTIONS)

• Using other medications:
  Consult your doctor or pharmacist if you are taking or have recently taken any other medication obtained with or without a prescription. This is especially important if you take medications containing:
  - Theophylline to treat asthma
  - Clozapine for schizophrenia
  - Ropinirole to treat Parkinson’s disease
  
  Consult your doctor before using this product if you have or have had heart, thyroid, circulation, stomach, throat or mouth problems, high blood pressure, or if you are taking insulin or any prescription medicine.
  Do not use for more than six (6) months without consulting a health care practitioner.
  Discontinue using this product and consult your doctor if irregular heartbeat, chest pain or leg pain occurs or if severe persistent stomach upset (indigestion, heartburn) develops.
  Consult your doctor if you have difficulty in reducing the quantity of nicotine.
• Consult your dentist or doctor if injury or irritation to the mouth, teeth or gum around dentures occurs.
• Keep out of reach of children and pets.
• Stop smoking, chewing tobacco or using snuff or any other nicotine replacement therapy products including patches before and while using this product since it may result in an overdose of nicotine.
• Do not use if you are under 18 years of age (the use of this product for children and adolescents who smoke has not yet been evaluated).
• Do not use if you are allergic to nicotine or any of the non-medicinal ingredients in this product.
• In case of overdose or if a child takes one or more nicotine mini-lozenges, contact your doctor or local Poison Control Centre at once. Children are especially sensitive to the effects of even small doses of nicotine. Symptoms of an overdose include nausea, abdominal pain, vomiting, diarrhea, cold sweat, dizziness, disturbed hearing and vision, mental confusion, rapid heartbeat, difficulty breathing and marked weakness.
• Do not use if you are pregnant or breastfeeding a child. Do not get pregnant while using this product. If you think you are pregnant stop using this product and consult your doctor.
• Do not use this product if you are an occasional smoker or non-smoker.

PRODUCT COMPOSITION

Medicinal ingredient in each dosage strength:

• Nic-Hit spray 1 mg: contains 1 mg nicotine per spray
• Nic-Hit spray 2 mg: contains 2 mg nicotine per spray

Non-medicinal ingredients:
propylene glycol, glycerol, xylitol, flavor, and purified water.

POSSIBLE SIDE EFFECTS

Nic-Hit spray can cause side effects, although not everyone gets them. Nic-Hit spray can give the same side effects as other ways of taking nicotine. The side effects generally depend on the dose you take.

• Effects related to stopping smoking (nicotine withdrawal)
  You may experience unwanted effects because by stopping smoking you have reduced the amount of nicotine you are taking. You may also experience these effects if you underuse the Nic-Hit spray before you are ready to reduce your nicotine intake.
• The side effects include:
  - Irritability, aggression, impatience or frustration
  - Feeling anxious, restlessness or having difficulty concentrating
  - Night time awakening or sleep disturbance
  - Increased appetite or weight gain
  - Feeling low
  - Urges to smoke (craving)
  - Lowering of heart rate
  - Bleeding gums
  - Dizziness
• Some effects are very common when using Nic-Hit spray, affecting more than 1 in 10 individuals:
  - Hiccups (these are particularly common)
  - Headache, nausea (feeling sick)
  - Local effects of the spray such as tingling, burning sensations, inflammation or pain in the mouth or lips or changes in taste perception
  - Dryness of the mouth or throat or conversely increased amounts of saliva
  - Feelings of dyspepsia (indigestion)
• Some effects are common, affecting between 1 in 10 and 1 in 100 individuals
  - Cough
  - Pain or discomfort in abdomen or chest
  - Vomiting, flatulence or diarrhea
  - Tightness or numbness of the throat
  - Feeling tired (fatigue)
• A number of side effects have been uncommon, in between 1 and 100 and 1 in 1000 individuals:
  - Effects on the nose such as running, stuffiness, sneezing, bleeding or changes in how things smell
  - Wheezing (bronchospasm) or feeling like breathing requires more effort than usual (Dys pnea)
  - Skin flushing (blushing), tingling, increased sweating or cold sweats
  - Eye irritation and increased tear production (lacrimation)
  - Pain, tension or discomfort in the muscles or joints
  - Oral effects such as toothache, inflammation of the tongue or gums, damage to the lining of the mouth or changes in the sound of your voice.
  - Palpitations (an unusual awareness of your heart beating) or a fast heart rate
  - Decreased appetite
  - Hypersensitivity (allergy) including rash and/or itching (pruritus, urticaria) of the skin.
• A few side effects have been seen in small numbers of patients, but how common they are cannot be calculated from the data known:
  - A fast and/or irregular heart beat (atrial fibrillation)
  - Blurred vision
  When you stop smoking you may also develop mouth ulcers. The reason why this happens is unknown.
• If you experience a side effect that worries you, or if you have a side effect not listed in this guide, tell your professional health care provider or pharmacist.